Innovation isn't only a state of mind, it's also an intellectual effort to bring a new vision to an area, e.g. making energy efficient light bulb. That's why you need a good knowledge of the area to be able to go further than others.
|You wouldn't do it at home, so don't do it to your business! Associate with people who wil complement your skills|
If you choose a subject you don't master yet, you may never be as good as someone else who's already in the field.
Does that mean you can only choose domains you're an expert of? Of course not! Associate with someone who's got the right expertise.